HUMAN PAPILLOMA VIRUS

human papilloma virus

Many infections cause any symptoms in healthy people. The person who brought the virus to inhibit the activity of the immune system is a carrier of the infection. Transfer of this pathogen to other people that contain viral particles in biological fluids is even happening welfare because full clinical, the patient. The main reason may be hidden during infection, the spread of the disease is important: patients do not infect other people continue to pass the time without being aware of the survey.

Human papillomavirus (HPV) infectious agent is an example of what might be called the secret. Most people become infected throughout the life of at least one HPV type, however, is not the case whenever clinical symptoms arise. This remote complications such as infection, including doctors, that creates a high risk of a malignant tumor. Immunodeficiency of the patients who are suffering in this situation often arises, such a negative result is disease. Topical medications help suppress symptoms of HPV infection. Also, it is recommended to timely vaccination.

Learn more about the disease

Pathogen, human papillomavirus infection of skin and mucous membranes lethal organs. The main manifestation of the disease the growth of tumors in the area of the face, the genitals, mouth and throat. In some cases, genital papilloma of non-specific areas of the skin as upper and lower extremity. Localization depends on the type of wart HPV. The cause of the infection the infection most people carry concealed, however, lower immune the virus begins to show its virulence. In some cases, the immune cells are pathogenic in rats after 3-6 months of no body of their own.

The most common disease of HPV infection, sexually transmitted diseases. Such a figure can be described by high-a deadly virus pathology and asymptomatic in most people. The use of condoms to prevent infection, so the patient may continue to spread the virus-even for safe sex. At the same time, experts have developed effective vaccines to prevent the development of HPV natural form. Girls in adolescence because it illustrates immunization, virus protection is necessary in order to instill first sexual contact.

Virus features

Human papillomavirus is a pathogen that contains DNA. On the contrary, bacteria and other microorganisms, viruses are just genetic information in the cell after a dose of exercise is the core of private and burial activities. After that, the start of viral protein synthesis in the affected cell is necessary for mounting the particle. Almost all representatives of the human family is only one type of organisms and the attack of HPV infection can occur in people.

Scientists have known for more than 600 strains (species) of the human papilloma virus, different genetic information. Why defeat mucous membranes and skin HPV 40 different shapes. This classification has important clinical value, the degree of oncogenetic strains. So, cervical cancer, HPV types 16 and 18 in women the most common caused by the invasion. These infectious agents are always changes in the skin that is.

Basal layer of epithelium HPV effects of clothing. Related to the pathogen may be in the form of episome, in the cell, DNA, the genome of the cell or that is associated in an integrated manner. A fully integrated virus produces necessary protein, why not a clinical symptoms of illness. HPV, the body is not in livelihood, the reason the rebirth of the malignant tissue, however, a carrier virus, risk factors that increases the risk of cancer.

Ways infection

The concept of virus, basal epithelial cells, therefore, any minor injuries of skin and mucous membranes increases the risk of infection. Most HPV is passed during vaginal, anal or oral sexual contact. Condoms are the only part who can protect the surface of the skin, however, the body through penetration of the viral particles still don't get the other. The presence of genital warts to pathogen transfer, but the source of the disease are HPV carrier undamaged skin from the outside.

The other transmission path

  1. The infection of the baby during the birth. The most frequently occurring lesions of the respiratory tract in children
  2. Another body independent transport of a site with a virus
  3. General use items, including personal hygiene, razor, toothbrush and towels
  4. A blood transfusion. Recent research opportunity for transfusion transmission.
  5. Surgical intervention in non-sterile conditions

Though several reasons, virus infections, the only way genital infection of HPV has clinical value. Other sources of infection are characterized by, low risk, pathogen distribution.

Risk factors

As well as direct transmission routes, should also be taken into account the role of HPV, risk factors. In question, the lifestyles, people and certain physical conditions.

The key factors the risk of infection

  1. Many sexual partners. Even safe sex active sex life cause sooner or later infection.
  2. Age. Detect genital warts human papillomavirus infection in oral cavity and most of the time patients respiratory system that is characterized by adolescents and young children.
  3. A weak immune system. Patients who are suffering from acquired immune deficiency virus HIV infection or at high risk of invasion. Symptomatic is also the most common manifestation of HPV after organ transplantation.
  4. Corruption, skin, and mucous membranes. It's easy to look Mikrotravma virus infiltration, epithelial basal layer.
  5. Smoking and alcoholism. Active harmful habits that weaken immunity.
  6. Genitourinary infection.

In addition, infection risk group to go for pregnant women. It should be noted that an effective preventive strategy for Disease predisposition the problem.

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Clinical course

The incubation period preceding symptomatic disease symptoms can last a couple of months or not. During this time in patients with immune body, no infection, but the pathogen elimination is not spontaneous, happens all the time. Man, maybe at the same time infected with various virus strains. Under the influence of the negative factors that arise from HPV infection symptoms, weight loss, immune protection fabrics. Because of the repetitive discharge, genital warts, and from time to time is lost and re-shaped. Oncologic complications such as infection you may develop in a few decades.

The possible consequences of the disease:

  1. Carcinoma of the cervix malignant tumor of epithelial tissue. Such a only oncology human papillomavirus associated. Time, timely vaccination risk of oncogenesis is reduced.
  2. Squamous cell carcinoma of the anal hole. Such a complication can occur in both men and women. During the early symptoms of cancer are pain, bleeding and itching.
  3. Because of the violation of urination, urethral obstruction warts.
  4. Malignancy re-in the area of the wart, throat and mouth.

The most frequent causes of death, cervical cancer, woman. If you have a virus on this disease because of the regular passage surveys, if you have a gynecologist. Modern vaccine to protect women, oncogenic HPV types.

Diagnosis

Who wart survey of gynecologists, urologists, venereologists and dermatologists. During primary intake, the doctor asks about the patient's symptoms, examination of skin formation together familiar and he won. The symptoms of HPV are usually easily detected, but as necessary to rule out other diseases. Instrumental and laboratory studies will appoint an expert for this.

Necessary diagnostic methods:

  1. Vehicle inspection, vagina and the cervix (HPV). Mandatory screening for cervical carcinoma that such a study be done. During the examination, the doctor can detect epithelial dysplasia and papilloma multiple plots.
  2. Biopsy, in the field of fabric material, changes in the skin or mucous membranes. Saytolojik a working example that reveals malignant cells.
  3. Polymerase chain reaction – this HPV viral particles in the body. Holding that this test gives a doctor ability to identify pathogen strain and viral load.
  4. Digen to-test – this high-precision DNA oncogenic human papillomavirus strains. A study that is used as a reliable scan.
In addition to the features listed research, the doctor recommends the patient tests for other infectious diseases, including HIV and syphilis.

Medication treatment etc.

Drugs developed, allowing for HPV infection and prevent disease eliminate the symptoms only cancer tissue. Drugs with a complete virus elimination, etc, it is not possible for the treatment of. If assigned to oral and topical medications, high-risk, oncogenesis, cancer, myocardial infarction and other adverse conditions. If external changes are not sufficient preventive measures the virus itself is common.

Possible target

  1. Salicylic acid wart removal. That is used to skin treatment, face and genitals.
  2. Creams and ointments containing drugs regulatory of the immune system.
  3. Erythromycin – ointment cytotoxic action. Application pharmaceutical, etc the affected skin pathogenic factors leads to destruction.
  4. Acid powder, chemical etching, general and genital warts. Why an expression of the local cult.

The medicines listed should only be used under medical supervision. After you remove the wart HPV infection can occur again, and even spread to another area.

Surgical treatment

surgical treatment, human papilloma virus

The doctor can offer the patient underwent surgical and minimally invasive methods of wart removal. Typically, such methods why no complications, however, may occur in the early days after the operation bleeding tissue.

Kind of interference:

  1. normal surgical excision;
  2. follow up ice cream with liquid nitrogen destruction of the affected tissues;
  3. electrical coagulation;
  4. with laser mole removal.;
  5. radio frequency use "the knife".

All operations is performed under local anesthesia. The expert will choose the most secure genital warts treatment method.

Guess

Throughout human papillomavirus infection and immune status of the patient depends on the particular virus strain. 30% of the population caused by spontaneous elimination of the pathogen, active immunity due to illness. Symptomatic disease is usually self-pregnant women, children, the elderly, and immunocompromised patients.

To repetitive characteristic of HPV infection throughout. Papilloma of the skin or to fade slowly to spread in the neighboring areas. Natural virus strains most frequently hit, the lining of the uterus and cervix malignant epithelial dysplasia risk factors that increases the effects of like the texture of rebirth, cigarette smoking, and oral contraceptives. Infestations may occur 10-20 years later tumor virus in the body.

Prevention

The most reliable method of prevention, early indicated. Gardasil, the vaccine containing viral proteins and auxiliary components effective against HPV 6, 11, 16 and 18 types. If you can be vaccinated at an early age first sexual intercourse, risk of cervical cancer in women worldwide, then less than 1%.

More prevention:

  1. condom use;
  2. sexual intercourse only reliable partners;
  3. meticulous personal hygiene;
  4. gynecological examination at least once a year.